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Award details
Methodology for high through put characterisation of loci controlling complex traits in livestock.
Reference
BBS/E/R/00000679
Principal Investigator / Supervisor
Professor Dirk De Koning
Co-Investigators /
Co-Supervisors
Institution
The Roslin Institute
Department
The Roslin Institute Department
Funding type
Research
Value (£)
53,058
Status
Completed
Type
Institute Project
Start date
01/10/2003
End date
31/05/2004
Duration
8 months
Abstract
QTL mapping in livestock is currently facing two challenges: 1) the transition from experimental populations towards general pedigrees. 2) The use of new information sources like gene expression. We aim to provide tools to exploit new technology and accommodate different mapping designs in livestock: a) We will develop and implement high throughput analytical tools for the detection of interacting genomic loci affecting RNA abundance levels, starting from experimental designs. B) For general pedigrees, the variance component models will be extended to accommodate different genetical models and implemented for ongoing experiments. C) Anticipating more widespread use of microarrays in livestock, the implementation of variance component models for gene expression will be studied.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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