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Rational design of plant systems for sustainable generation of value-added industrial products (SmartCell)

Reference	BBS/E/J/000CA372
Principal Investigator / Supervisor	Professor Anne Osbourn
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	229,371
Status	Completed
Type	Institute Project
Start date	01/01/2009
End date	30/09/2013
Duration	57 months

Abstract

This project is part of the EU programme (Smartcell), the goal of which is to develop fundamental knowledge and enabling technologies so that plants and plant cells can be engineered to produce valuable secondary metabolites which can be successfully extracted and purified for industrial and medical uses. The use of post-genomic technologies and cutting edge systems biology approaches in the project aims to enhance the output of specific target molecules, aiming at production levels sufficient for industrial purposes. The overall focus of SmartCell is on monoindole alkaloids (MIAs) produced by Madagascan periwinkle. The JIC part of this project will involve the identification and validation of genes required for synthesis of terpenes in plants with specific emphasis on identification of genes and enzymes for MIA modification, using a combination of a candidate gene approach, heterologous expression (using a plant virus-based expression system), and a resource of plant mutants.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	Crop Science, Plant Science, Synthetic Biology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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