Award details

Defining functional components of the plasmodesmal proteome

Reference	BBS/E/J/000CA277
Principal Investigator / Supervisor	Professor Andrew Maule
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	150,218
Status	Completed
Type	Institute Project
Start date	01/11/2006
End date	31/10/2009
Duration	36 months

Abstract

Plasmodesmata are the conduits for macromolecular trafficking between plant cells and therefore play an important role in plant development and plant defence. They are complex, membrane-rich channels that traverse the cell wall to maintain symplastic continuity between adjacent cells. Despite their importance virtually nothing is known about their molecular constituents or the mechanisms whereby cell-to-cell communication is achieved. This project aims to identify new plasmodesmal proteins from purified primary plasmodesmata isolated from Arabidopsis suspension cells. The approach will improve on recent successes we have had in using advanced proteomic technologies on cell wall preparations for the identification of plasmodesmal proteins. Using genetic, molecular and biochemical approaches, the roles of these proteins, and a group of previously identified plasmodesmal proteins, in macromolecular trafficking will be established. This work will shine a light on one of the remaining great mysteries in plant biology / macromolecular trafficking from cell to cell.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	Plant Science
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search