Award details

Cloning wheat rust resistance genes by sequence capture on structured populations

Reference	BBS/E/J/000C0673
Principal Investigator / Supervisor	Professor Brande Wulff
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	232,092
Status	Completed
Type	Institute Project
Start date	01/07/2014
End date	31/03/2017
Duration	32 months

Abstract

Rust resistance genes in cereal crops are often overcome within a few seasons when deployed one at a time. Introgressing multiple resistance genes into a cultivar is one strategy that may contribute to more durable resistance; however, when this process is done by traditional breeding methods it involves long breeding trajectories and can result in linkage drag due to deleterious alleles. We are pursuing a transgenic approach to control wheat stem rust. Our strategy is to isolate multiple novel stem rust resistance (Sr) genes and deploy them in combination at a single transgene locus in wheat. This strategy should avoid linkage drag and ensures that the genes stay together, thus avoiding single genes again being exposed to the pathogen. This project will support our ongoing efforts to combine targeted sequence capture, high throughput sequencing and comparative genomics on genetically structured populations to speed up the cloning of Sr genes from diploid relatives of wheat and from wheat alien introgression lines.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Crop Science, Microbiology, Plant Science
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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