Award details

CDR1-mediated peptide signalling in Arabidopsis disease resistance

Reference	BBS/E/J/0000A229
Principal Investigator / Supervisor	Professor Chris Lamb
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	194,026
Status	Completed
Type	Institute Project
Start date	01/03/2005
End date	29/02/2008
Duration	36 months

Abstract

Plants are continually exposed to a wide array of potential pathogens and have evolved a battery of protective disease resistance mechanisms. Although disease is the exception rather than the rule, when protective mechanisms break down the consequences can be devastating with major crop losses pre- and post-harvest. Crops can be protected with agrochemicals but these are expensive, prohibitively so for developing country farmers, and also generate an environmental load directly and from the energy used for application. The present research is based on the premise that understanding natural disease resistance mechanisms will provide the basis for new strategies to deliver crop protection more sustainably either through the development of new non-toxicant agrochemicals or more likely through genetic delivery of enhanced durable disease resistance. Recent work in my laboratory has led to the discovery of a novel mechanism for disease resistance signalling in plants. This mechanism resembles some aspects of signalling in animals whereby specific enzymes release small peptides as key signal molecules. The aim of the present grant is to find out more about how this plant peptide signal system works- the nature of the peptide, what protein it is released from, where it is located in the plant, where it fits in the overall signal network. This work will allow us to figure out how the plant perceives the signal and responds by becoming more hardy.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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