Award details

Trans-cis elements regulating key switches in plant development (TRANSISTOR)

Reference	BBS/E/J/0000A228
Principal Investigator / Supervisor	Professor Robert Sablowski
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	130,310
Status	Completed
Type	Institute Project
Start date	01/03/2005
End date	28/02/2009
Duration	48 months

Abstract

Biology increasingly depends on genomics, requiring biologists to become proficient in bioinformatics and biostatistics. The project addresses this need, helping the European Research Area to achieve critical mass at the interface between developmental genetics, genomics and bioinformatics. We use regulatory genes, controlled by inducible systems, to trigger key steps in flower, fruit and seed development. Microarray technology will reveal changes in expression of thousands of genes at once. This data will be used by bioinformatics specialists to find co-regulated genes. The promoters of these genes will be analysed for common cis-elements in their promoters. A series of experiments will be conducted to elucidate the promoter architecture of the identified genes and the factors that bind to their promoters. Furthermore, the biological relevance of these interactions will be studied.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	Plant Science
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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