Award details

Systems Biology of Stem Cell Function in Arabidopsis thaliana (SY-STEM)

Reference	BBS/E/J/0000A216
Principal Investigator / Supervisor	Professor John Doonan
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	98,792
Status	Completed
Type	Institute Project
Start date	01/01/2005
End date	31/12/2008
Duration	48 months

Abstract

Cellular processes such as cell division, cell expansion and protein translation, provide the basis for organ and organism growth. The cell cycle involves at least two phases, S-phase when the genome is replicated and mitosis when the genome is separated. During mitosis, nuclear architecture is severely re-arranged to allow for genome separation and many essential functions, such as translation, are modified or suspended. Coordinated and differential regulation of such functions during the cell cycle are important for both the cell and the organism. Using a biochemical approach to isolate protein complexes, we have found a link that may couple protein translation with cell cycle regulators. In this project we will explore the role of this link in regulating protein production during the cell division cycle.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	Plant Science
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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