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Role of ROOT HAIR DEFECTIVE2 in cell growth

Reference	BBS/E/J/0000A184
Principal Investigator / Supervisor	Professor Liam Dolan
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	167,572
Status	Completed
Type	Institute Project
Start date	09/09/2004
End date	29/07/2008
Duration	47 months

Abstract

A major factor in the development of cell shape is the spatial regulation of growth. We discovered that reactive oxygen species (ROS) produced by RHD2/AtrbohC control cell growth in the root. The sub-cellular distribution of ROS indicates that the spatial distribution of ROS dictates the sites of growth on a cell. We therefore predict that the spatial distribution of RHD2/AtrbohC protein or its activators controls the location of the sites of cell growth. The aims of this proposal are to 1) determine the distribution of RHD2/AtrbohC in growing cells 2) determine if RHD2/AtrbohC physically interacts with ROP GTP-ases which are located at growing points 3) to identify other members of the RHD2/AtrbohC gene family that regulate cell growth. A major factor in the development of cell shape is the spatial regulation of growth. We discovered that reactive oxygen species (ROS) produced by RHD2/AtrbohC control cell growth in the root. The sub-cellular distribution of ROS indicates that the spatial distribution of ROS dictates the sites of growth on a cell. We therefore predict that the spatial distribution of RHD2/AtrbohC protein or its activators controls the location of the sites of cell growth. The aims of this proposal are to 1) determine the distribution of RHD2/AtrbohC in growing cells 2) determine if RHD2/AtrbohC physically interacts with ROP GTP-ases which are located at growing points 3) to identify other members of the RHD2/AtrbohC gene family that regulate cell growth.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	Plant Science
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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