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Molecular action of FRIGIDA in repression of the floral transition

Reference	BBS/E/J/0000A170
Principal Investigator / Supervisor	Professor Dame Caroline Dean
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	111,783
Status	Completed
Type	Institute Project
Start date	03/11/2003
End date	26/08/2007
Duration	46 months

Abstract

FRI causes plants to over-winter before flowering. FRI represses flowering by increasing RNA levels of the floral repressor, FLC and this function is antagonised by vernalization. Given the involvement of a Polycomb-type mechanism in vernalization, we will test whether FRI functions like trithorax-group proteins to regulate FLC chromatin structure. We will use sector analysis to determine if FRI is required during a particular developmental window and chromatin immunoprecipitation to ask if FRI is associated with changes in the histone code at FLC. We will determine if FLC is a direct target of FRI and identify proteins interacting with FRI through Y-2-H assays/plant functional analyses and affinity purification of complexes from plants.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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