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Dynamic Growth Maps of Development
Reference
BBS/E/J/0000A169
Principal Investigator / Supervisor
Professor Enrico Coen
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
John Innes Centre Department
Funding type
Research
Value (£)
136,038
Status
Completed
Type
Institute Project
Start date
02/02/2004
End date
01/02/2007
Duration
36 months
Abstract
The aim is to provide an experimental, computational and theoretical framework to help bridge the gap between gene function and the development of shape. A combination of approaches will be used to derive quantitative dynamic growth maps in three developmental systems ¿ the Arabidopsis leaf, Drosophila wing and mouse limb. This will involve tracking cells over time in 2D or 3D and clonal analysis to estimate regional growth parameters and organ shapes resulting from growth and/or rearrangements of cells. Dynamic maps will be developed that show the pattern of growth over space and time. These will be used together with knowledge of gene activities to derive testable predictive models for key components governing the development of shape.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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