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Targeting immunocomplex production in plants
Reference
BBS/E/J/0000A091
Principal Investigator / Supervisor
Professor George Lomonossoff
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
John Innes Centre Department
Funding type
Research
Value (£)
187,966
Status
Completed
Type
Institute Project
Start date
01/09/2002
End date
31/08/2005
Duration
36 months
Abstract
The overall objective of this project is the large scale production in plants of targeting immunostimulating structures. These are designed as generic vehicles to allow the oral immunisation of pigs against a number of important pathogens. The project consists of three principle components: (1) The construction of immunostimulating-structures which can target antigens to the enteric tract (2). The expression of immunostimulating-structures at high levels in plants using recently developed ¿plant replicon¿ systems (3). Analysis of the efficacy and safety of the plant-derived immunostimulating-structures and a comparison with the properties of the material expressed in mammalian cells.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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