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Molecular dissection of the role of FCA and FY in the floral transition
Reference
BBS/E/J/0000A080
Principal Investigator / Supervisor
Professor Dame Caroline Dean
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
John Innes Centre Department
Funding type
Research
Value (£)
42,851
Status
Completed
Type
Institute Project
Start date
20/01/2003
End date
19/01/2006
Duration
36 months
Abstract
The autonomous promotion pathway plays a major role in controlling the floral transition in Arabidopsis. Its main function is to down-regulate RNA levels of the floral repressor, FLC. The Dean lab has cloned two components of this pathway, FCA and FY, which encode an RNA-binding protein and a homologue of a yeast protein required for mRNA 3'-end- processing and polyadenylation respectively. We have recently shown that FCA:FY proteins interact physically and regulate the alternative processing of the FCA transcript. We now aim to analyse how FCA:FY regulate FLC, characterise other cellular targets of FCA:FY and define the components of the FCA:FY complex through the complementary approaches of protein interaction assays and suppressor mutagenesis.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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