Award details

Discovery and functional analysis of the starch proteome

Reference	BBS/E/J/0000A053
Principal Investigator / Supervisor	Professor Alison Smith
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	82,214
Status	Completed
Type	Institute Project
Start date	01/07/2002
End date	01/07/2005
Duration	36 months

Abstract

Understanding of the enzyme and proteins involved in starch synthesis and degradation is far from complete. The aim of this project is to use genomic resources available in Arabidopsis to discover new components of the starch proteome. The approaches include the discovery and gene-identification of new phenotypic mutants using novel screens (e.g. FTIR), the re-mutagenesis of existing mutants with altered starch metabolism, the use of in vivo tagging followed by MALDI-ToF MS to isolate and characterise complexes of proteins involved in starch metabolism, and proteomic approaches to identifying all of the proteins associated with the starch granule. The characterisation of mutants affected in the newly-discovered genes will enable us to make progress in previously intractible areas of starch metabolism - for example starch granule initiation and the control of starch degradation.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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