Award details

Probing the host response to plant virus attack

Reference	BBS/E/J/0000A047
Principal Investigator / Supervisor	Professor Andrew Maule
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	83,422
Status	Completed
Type	Institute Project
Start date	06/06/2002
End date	05/09/2006
Duration	51 months

Abstract

All plants can become infected by viruses. However, the severity of the infection is balanced by the ability of the host to mount a defence response. The aim of this project is to monitor the molecular changes in the host that occur following infection and to analyse those changes with respect to the positive demands of the virus for multiplication and the defence-related responses. This will be achieved using two technical innovations. The first is to establish a system whereby all the cells in a plant tissue or cell culture multiply the virus in synchrony. This will provide a more accurate report on molecular changes than has been achieved previously. And second, is to develop a microarray technical platform for a highly permissive host for virus replication such that changes in the activity of thousands of genes in parallel can be measured following infection.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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