Award details

Exploitation of a novel Sec-independent secretion pathway for protein production

Reference	BBS/E/J/00004302
Principal Investigator / Supervisor	Professor Tracy Palmer
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	48,360
Status	Completed
Type	Institute Project
Start date	01/02/2000
End date	31/01/2003
Duration	36 months

Abstract

Although the general secretory (Sec) pathway has enormous potential for protein production (see: the EBSG section), it is presently inapplicable for the export of a large variety of high value-added proteins. Recent studies, primarily by this partnership, have revealed the operation of a novel Sec-independent bacterial protein export system, which has the specific ability to export proteins that are synthesised with signal peptides bearing twin-arginine motifs (RR-signal peptides). The ExporteRRs consortium will develop technologies and expertise required for the exploitation of the Tat pathway for protein production

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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