BBSRC Portfolio Analyser
Award details
Degradation of organophosphorous pesticides by bacteria
Reference
BBS/E/J/00004229
Principal Investigator / Supervisor
Professor Mike Merrick
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
John Innes Centre Department
Funding type
Research
Value (£)
73,855
Status
Completed
Type
Institute Project
Start date
01/08/2000
End date
31/07/2003
Duration
36 months
Abstract
Flavobacterium balustinum is capable of utilising methylparathion as sole carbon source. The enzyme responsible for degradation is parathion hydrolase, the structural gene for which (opd) we have shown to be carried on a plasmid in this organism and to be closely related to other opd genes previously isolated in the USA and the Phillipines. This project will develop our studies on organophosphate degradation in a number of directions: investigations into the role of the signal sequence in membrane targeting of the enzyme; studies on the mechanisms that regulate expression of parathion hydrolase at the transcriptional or translational levels; studies on the possible roles of other gene that are closely linked to opd.
Summary
unavailable
Committee
Closed Committee - Engineering & Biological Systems (EBS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search