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Regulation of fatty acid synthesis
Reference
BBS/E/J/00003713
Principal Investigator / Supervisor
Dr Matthew Hills
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
John Innes Centre Department
Funding type
Research
Value (£)
8,442
Status
Completed
Type
Institute Project
Start date
01/04/1997
End date
10/03/2000
Duration
35 months
Abstract
This work aims to develop an in depth understanding of the regulation of fatty acid synthesis in plastids isolated from Brassica napus. We have shown that acyl-CoA, the final product of fatty acid synthesis by the plastid causes inhibition of fatty acid synthesis if it is not remove by acyl-CoA binding protein. It is thought that in vivo this protein transfers the acyl-CoA from the plastid to the ER where it is converted into storage oil. We will be studying this regulation in depth in plastids from embryos and comparing the plastid system with regulation of fatty acid synthesis in chloroplasts isolated from leaves. Once the regulation of the pathway fatty acid synthesis is fully understood, rational approaches to its manipulation can be undertaken.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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