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Immunotherapy of enteric infections by rotoviruses and cornoviruses using plantibodies
Reference
BBS/E/J/00001416
Principal Investigator / Supervisor
Professor George Lomonossoff
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
John Innes Centre Department
Funding type
Research
Value (£)
85,347
Status
Completed
Type
Institute Project
Start date
01/10/2000
End date
30/09/2003
Duration
36 months
Abstract
This project is funded under the EC Framework 5 programme and involves laboratories from the U.K. (John Innes Centre), Spain (Centro Nacional de Biotecnologia, Madrid), Italy (Internation Centre for Genetic Engineering and Biotechnology, Trieste) and Germany (Institut fur Biologie I, Aachen). The overall objective is the large-scale production of immuno-therapeutic antibodies against enteric diseases of both farm animals and humans at sufficiently low cost for their widescale use to be a practical proposition. To this end, antibodies against two important enteric pathogens, corona- and rotaviruses, will be expressed in plants and their ability to confer protection aginst infection of newborn animals will be assessed. The research at the John Innes Centre involves the expression of antibody chains in plants using vectors based on Cowpea mosaic virus (CPMV)
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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