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Role of the KOJAK gene in cell wall formation in plants

ReferenceBBS/E/J/00001328
Principal Investigator / Supervisor Professor Liam Dolan
Co-Investigators /
Co-Supervisors
Institution John Innes Centre
DepartmentJohn Innes Centre Department
Funding typeResearch
Value (£) 22,891
StatusCompleted
TypeInstitute Project
Start date 24/01/2001
End date 23/01/2003
Duration24 months

Abstract

Kojak mutants have short root hairs that lyse and the mature plant is smaller in stature than wild type, indicating that KJK is required for cell wall biosynthesis in the root hair and throughout the plant. We have cloned KJK, and as expected, it encodes a member of the cellulose synthase family of genes (AtCslD3). kjk1 and kjk3 alleles have premature stop codons resulting translation of an attenuated protein while there is a V-M mutation at the active site in the kjk-2 allele. All are predicted to be complete loss of function mutations. The aim of the present proposal is to characterise the role for this in cell wall formation in Arabidopsis using the root hair as a model using a structural approach.

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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