Award details

Molecular organisation of rDNA transcription complexes

ReferenceBBS/E/J/00001309
Principal Investigator / Supervisor Professor Peter Shaw
Co-Investigators /
Co-Supervisors
Institution John Innes Centre
DepartmentJohn Innes Centre Department
Funding typeResearch
Value (£) 10,440
StatusCompleted
TypeInstitute Project
Start date 01/11/1997
End date 31/10/2000
Duration36 months

Abstract

We aim to determine the ultrastructural organization of active RNA polymerase I transcription complexes by a combination of different microscopies (confocal, TEM, tilted view reconstruction, TEM of replicas). We will determine their structures both in their native conformation in well-preserved (rapidly frozen) cells and at differing degrees of disruption by hypertonic and physical spreading, in order to arrive at a detailed picture of the native, active conformation.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
terms and conditions of use (opens in new window)
export PDF file