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Seeking the key target gene through which a tRNA regulates Streptomyces differentiation
Reference
BBS/E/J/00001246
Principal Investigator / Supervisor
Professor Keith Chater
Co-Investigators /
Co-Supervisors
Institution
John Innes Centre
Department
John Innes Centre Department
Funding type
Research
Value (£)
3,255
Status
Completed
Type
Institute Project
Start date
04/01/1999
End date
03/01/2002
Duration
36 months
Abstract
The 64 triplet arrangements of the 4 different bases of DNA and RNA have 21 meanings in the genetic code. Thus, TTA is one of 6 triplets encoding the amino acid leacine in proteins. Uniquely in Streptomyces bacteria, which are the most important source of antibiotics, this triplet is not used for normal growth, but it is used in some gene(s) essential for antibiotic production and spore formation. We aim to identify and study the gene(s) essential for sporulation.
Summary
unavailable
Committee
Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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