Award details

Trehalose, stress and sporulation

Reference	BBS/E/J/00001231
Principal Investigator / Supervisor	Professor Keith Chater
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	94,588
Status	Completed
Type	Institute Project
Start date	17/01/2000
End date	16/01/2003
Duration	36 months

Abstract

The morphologically complex organism Streptomyces coelicolor invests probably at least 14 genes in partitioning glucose between the stress-protecting disaccharide trehalose, the storage polysaccharide glycogen, and central metabolism. We propose to study (a) the temporal and spatial control of a subset of these genes during development and in response to stress treatments, in the wild-type and selected developmental mutants; (b) the effects of these changes in gene expression, and of deleting or modifying the genes, on trehalose and glycogen levels, stress resistance and normal development. The results should give an unusually integrated view of the way that stress responses are built into normal biology and metabolism. They may also be relevant to carbon flux in relation to antibiotic production

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search