Award details

The Wbl protein family: its potential for wide-ranging insights into actinomycete biology

Reference	BBS/E/J/00001224
Principal Investigator / Supervisor	Professor Keith Chater
Co-Investigators / Co-Supervisors
Institution	John Innes Centre
Department	John Innes Centre Department
Funding type	Research
Value (£)	83,158
Status	Completed
Type	Institute Project
Start date	13/10/1998
End date	02/02/2002
Duration	40 months

Abstract

The aim of this proposal is a basic characterisation of the role of wbl genes in actinomycetes, which include many organisms of great industrial, environmental or medical importance. The wbl genes are a newly discovered gene family so far peculiar to actinomycetes (including pathogenic mycobacteria and industrially important streptomycetes). Their paradigm is whiB, a sporulation regulatory gene in Streptomyces coelicolor. An understanding of the expression of these genes and the evaluation of the structure and role of their products is expected to provide insights into unique physiological characteristics of actinomycetes, with potential benefits for industry, medicine and bioremediation.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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