Award details

Integrative Biology

Reference	BBS/E/I/00001942
Principal Investigator / Supervisor	Dr Paolo Ribeca
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	725,662
Status	Completed
Type	Institute Project
Start date	06/10/2014
End date	31/03/2017
Duration	29 months

Abstract

Modern high-throughput techniques (DNA/RNA-sequencing, ChIP-sequencing, ribosome profiling, mass-spectrometry) and subsequent high-performance bioinformatics data analysis have revolutionized the way we understand biology. The Integrative Biology project at the Pirbright Institute aims to put together in a problem-dependent way a number of such techniques, in order to precisely interrogate at each time point a set of compartments of the cell and hence gain a better overall understanding of its inner workings during the whole duration of the biological process. System studied will be the animal virology ones found at Pirbright. In fact, thanks to the extraordinary mechanisms of action of viruses such systems offer a privileged probing window into the operation of the basic mechanisms of the cell; at the same time, the usage of animal models allows for a direct testing of scientific hypotheses in vivo. In order to set up protocols suitable for the high-precision study of the main biological systems available at Pirbright, the project will be constantly exchanging knowledge and expertise with all the many relevant groups existing both inside and outside the institute.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Animal Health, Technology and Methods Development
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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