Award details

Multiscale modelling of viral diseases of livestock

ReferenceBBS/E/I/00001717
Principal Investigator / Supervisor Dr Simon Gubbins
Co-Investigators /
Co-Supervisors
Dr David Schley, Dr Anthony Wilson
Institution The Pirbright Institute
DepartmentThe Pirbright Institute Department
Funding typeResearch
Value (£) 1,058,814
StatusCompleted
TypeInstitute Project
Start date 01/04/2012
End date 31/03/2017
Duration59 months

Abstract

Biological processes occur at multiple scales, ranging from the molecular level to whole populations. Mathematical modelling provides a powerful tool for understanding these processes and for integrating them across scales. In this project we will develop mathematical models for the dynamics of viral diseases of livestock at a range of scales. In addition, we will develop appropriate statistical methodologies to estimate parameters and draw robust inferences about the underlying biological processes. Examples include: scaling from transmission experiments to spread of viruses within farms to spread at a regional level; characterizing the influence of antigen properties on the immune response in cattle; quantifying the risk of transmission from airborne spread and livestock movements; and investigating the mechanics of protein-induced viral-budding.

Summary

unavailable
Committee Not funded via Committee
Research TopicsAnimal Health, Immunology, Microbiology
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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