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Award details
Multiscale modelling of viral diseases of livestock
Reference
BBS/E/I/00001717
Principal Investigator / Supervisor
Dr Simon Gubbins
Co-Investigators /
Co-Supervisors
Dr David Schley
,
Dr Anthony Wilson
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
1,058,814
Status
Completed
Type
Institute Project
Start date
01/04/2012
End date
31/03/2017
Duration
59 months
Abstract
Biological processes occur at multiple scales, ranging from the molecular level to whole populations. Mathematical modelling provides a powerful tool for understanding these processes and for integrating them across scales. In this project we will develop mathematical models for the dynamics of viral diseases of livestock at a range of scales. In addition, we will develop appropriate statistical methodologies to estimate parameters and draw robust inferences about the underlying biological processes. Examples include: scaling from transmission experiments to spread of viruses within farms to spread at a regional level; characterizing the influence of antigen properties on the immune response in cattle; quantifying the risk of transmission from airborne spread and livestock movements; and investigating the mechanics of protein-induced viral-budding.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
Animal Health, Immunology, Microbiology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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