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Molecular and genetic determinants of virus-host interactions affecting pathogenicity
Reference
BBS/E/I/00001712
Principal Investigator / Supervisor
Dr Mark Fife
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
1,082,979
Status
Completed
Type
Institute Project
Start date
01/04/2012
End date
31/03/2017
Duration
59 months
Abstract
IAH has a distinct genetic resource of a number of inbred lines of chickens, which differ in their susceptibility to avian viral diseases. The availability of SNP (single nucleotide polymorphism) and CNV (copy number variation) data highlighting the genetic differences and the recent progress in the determination and the analysis of the data from re-sequencing of the genomes of these lines will enable us to make significant progress in understanding the molecular basis for the genetic differences that account for disease susceptibility. The Genetics and Genomics group will undertake detailed genetic analysis of the genomes of these unique lines to identify the determinants that are linked to disease resistance.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
Animal Health
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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