Award details

Development of a BRSV-ISCOM DIVA vaccine and corresponding DIVA test for future creation, identification and protection of BRSV free zones

Reference	BBS/E/I/00001557
Principal Investigator / Supervisor	Dr Geraldine Taylor
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	42,160
Status	Completed
Type	Institute Project
Start date	03/01/2012
End date	02/01/2015
Duration	36 months

Abstract

A strict control on which viral proteins will be included in the vaccine will open up possibilities to design a DIVA-vaccine that will enable to distinguish infected from vaccinated animals. Accordingly, a LUMINEX assay will be developed, based on a viral protein that is not included in the vaccine. This assay will detect IgG and IgM antibodies in serum only from animals that have been infected with the virus, but not from vaccinated, non-infected animals. Our belief is that a DIVA vaccine that induces full protection against BRSV shedding, and a corresponding IgG /IgM DIVA test, could be used to create, identify and protect BRSV negative herds.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Animal Health, Immunology, Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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