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Understanding FMDV persistence in African buffalo
Reference
BBS/E/I/00001523
Principal Investigator / Supervisor
Dr Nicholas Juleff
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
38,300
Status
Completed
Type
Institute Project
Start date
01/02/2011
End date
31/01/2015
Duration
48 months
Abstract
We have recently identified depots of non-replicating FMDV in lymphoid tissue draining the head and neck of cattle [13], sheep and buffalo after recovery from acute infection . The focus of this proposal is to determine whether these depots act as an archive of the population of viruses that have circulated in the animal since the onset of infection. A diverse population of viruses may be present in these depots as a result of the complexity of the initial inoculums, mutations and recombination occurring during virus replication and repeated infection with multiple strains and serotypes.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
Animal Health, Microbiology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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