Award details

Exploiting African swine fever virus surface proteins to develop rapid diagnostic tests and understand virus host interactions

Reference	BBS/E/I/00001488
Principal Investigator / Supervisor	Dr Linda Dixon
Co-Investigators / Co-Supervisors	Dr Geraldine Taylor
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	35,437
Status	Completed
Type	Institute Project
Start date	01/09/2010
End date	31/08/2013
Duration	36 months

Abstract

African swine fever virus is a complex DNA virus which contains more than 50 proteins in the multi-layered virus particle. Reagents for effective control of ASF including rapid diagnostic tests and vaccines are not currently available. In this project we will characterise the virus proteins on the surface of the extracellular enveloped and the intracellular mature virus particles. Reagents generated to these proteins will be used to study mechanisms of virus entry, to develop lateral flow devices for pen-side diagnosis and to evaluate immune responses against the proteins in pigs. This will identify targets for vaccine development.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Animal Health, Immunology, Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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