Award details

Development of an improved (DIVA) vaccine against peste des petits ruminants and technology for a control strategy in endemic areas

Reference	BBS/E/I/00001487
Principal Investigator / Supervisor	Dr Michael Baron
Co-Investigators / Co-Supervisors	Dr Geraldine Taylor
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	28,065
Status	Completed
Type	Institute Project
Start date	04/11/2010
End date	03/06/2014
Duration	43 months

Abstract

To create fowlpox-based candidate DIVA vaccines against PPRV, establish the degree of immune response of these vaccines and the optimal set of proteins to express from the recombinant. To set up appropriate C-ELISAs that recognise infection and/or vaccination separately. To develop flow-capture-based penside tests for PPRV antigen. In Uganda: To conduct the field trial of the candidate DIVA vaccine against PPR. To characterize the strains of PPRV circulating, and their extent of spread, in Uganda (genetic analysis). To validate the next generation of ELISA tests to differentiate vaccinated from infected animals (DIVA tests). To validate penside diagnostic tests for PPR. To introduce real-time PCR for the diagnosis of PPR and sheep/goat pox into the lab in Uganda.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Animal Health, Immunology, Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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