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Anticoccidial vaccine development: the importance of genetic diversity and delivery strategy

Reference	BBS/E/I/00001485
Principal Investigator / Supervisor	Professor Fiona Tomley
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	29,700
Status	Completed
Type	Institute Project
Start date	27/09/2010
End date	25/10/2010
Duration	1 months

Abstract

Coccidiosis is a devastating disease of poultry and other livestock caused by protozoan parasites of the genus Eimeria. Cost-effective, multi-valent recombinant vaccines are a realistic prospect following the identification of immunoprotective parasite antigens and development of parasite transfection technologies. To predict the likely efficacy and longevity of such vaccines in the field it is important to know the prevalence of naturally-occurring genetic (antigenic) diversity, rate of multiple infections, and frequency of genetic exchange between parasites. It is crucial also to have strong geographical networks in place, both for collecting parasites for the laboratory studies outlined above and to ensure efficient dissemination, delivery and support of traditional and new therapeutics (drugs and vaccines) to the world's poorest rural economies.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Animal Health, Immunology, Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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