Award details

Determination of the role of hard (Ixodid) ticks in the transmission of lumpy skin disease virus in cattle

Reference	BBS/E/I/00001484
Principal Investigator / Supervisor	Ms Eeva Tuppurainen
Co-Investigators / Co-Supervisors	Professor Philip Mellor, Dr Chris Oura
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	79,409
Status	Completed
Type	Institute Project
Start date	01/04/2010
End date	31/05/2013
Duration	38 months

Abstract

The aim of the proposed research is to investigate the transmission of lumpy skin disease virus (LSDV) between cattle by different life stages of A. hebraeum, R. appendiculatus and B. decoloratus ticks. All of these ticks are common in Africa. Laboratory-bred larvae, nymphs and adults will be placed to feed on the skin of the cattle experimentally infected with LSDV. Post feeding the partially engorged adult R. appendiculatus and A. hebraeum males, and larvae hatched from eggs laid by females, previously fed on the skin lesions of cattle with LSD, will be transferred to feed on the skin of non-infected recipient animals. Infected A. hebraeum and R. appendiculatus nymphs will be allowed to moult to adults and then transferred to feed on the skin of non-infected cattle. The recipient animals will be monitored for clinical signs of LSD. Samples will be collected at regular intervals to detect viraemia and seroconversion, and live virus in the skin of the previously non-infected animals. Also, the possible transmission of LSDV from infected to non-infected ticks by co-feeding on non-viraemic hosts, the survival mechanisms of the virus during the moulting of the ticks, the types of tick cells in which the virus multiplies and, the possible presence of virus in tick salivary glands, the cells of the midgut and eggs will be investigated.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Animal Health, Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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