Award details

Virology and vaccinology of negative-strand RNA viruses

ReferenceBBS/E/I/00001433
Principal Investigator / Supervisor Dr Michael Baron
Co-Investigators /
Co-Supervisors
Institution The Pirbright Institute
DepartmentThe Pirbright Institute Department
Funding typeResearch
Value (£) 316,116
StatusCompleted
TypeInstitute Project
Start date 01/07/2009
End date 31/03/2012
Duration33 months

Abstract

This project is the leadership, direction and management of the work of a group of PhD students and other science staff, primarily externally funded. The work of the group can be divided into two major parts: (i) the understanding of the basic molecular virology of specific viruses that cause livestock disease, the way the viruses replicate, their dependency on specific host proteins and the mechanisms employed by these viruses to counteract host innate immune responses; (ii) the creation of improved vaccines and tests for diseases of economic importance, in collaboration with institute immunologists and the reference laboratories in the Epidemiology division. The aims of the project are an improved understanding of the mechanisms by which different groups of viruses interact with the host, both at the cell and organism level, and how this may govern pathogenicity and host specificity, and the practical application of molecular biology techniques to the creation or improvement of vaccines against diseases caused by viruses in these groups. My work is to (a) teach PhD students and direct them in projects that ontribute to these aims, as well as examining and tutoring the students of other supervisors in the institute; (b) develop grant applications for funding that will support the project aims, and then direct the staff funded by those grants; (c) work with other senior staff to manage the laboratory spaces and codes of practice to ensure adequate and compliant working environment for the research to be carried out by the staff and students in the group.

Summary

unavailable
Committee Not funded via Committee
Research TopicsAnimal Health, Immunology, Microbiology
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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