Award details

Dissecting the role of the Campylobacter haem uptake system in host colonisation and disease

Reference	BBS/E/I/00001384
Principal Investigator / Supervisor	Professor Mark Stevens
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	72,137
Status	Completed
Type	Institute Project
Start date	01/01/2010
End date	31/08/2010
Duration	8 months

Abstract

A clear understanding of the determinants and processes involved in intestinal colonization of poultry is essential for the design and implementation of strategies to reduce the frequency of foodborne disease due to Campylobacter spp. In addition, comparing host-bacterial interactions in different models may highlight the basis for the clinical differences that exist between humans and poultry. There is clear evidence that high affinity iron acquisition systems are essential determinants for successful intestinal colonisation by Campylobacter jejuni. However, this evidence is only applicable to one group of strains. This proposal seeks to determine the role and function of the uptake systems which are required for intestinal colonisation of another major group of Campylobacter spp.

Summary

unavailable

Committee	Not funded via Committee
Research Topics	Animal Health, Microbial Food Safety, Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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