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Virus and host genes involved in re-programming of macrophage transcription in response to high and low virulence African swine fever virus isolates
Reference
BBS/E/I/00001235
Principal Investigator / Supervisor
Dr Linda Dixon
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
331,627
Status
Completed
Type
Institute Project
Start date
01/05/2006
End date
28/02/2011
Duration
58 months
Abstract
The specific objectives of the project are to 1) identify the virus-encoded proteins that cause decreased expression of host immunomodulatory genes at late time post-infection with a high virulence African swine fever virus isolate; 2) investigate the consequences on macrophage function of the increased expression of specific cell surface and secreted proteins during infection with ASFV isolates of high and low virulence.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
Animal Health, Immunology, Microbiology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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