Award details

Dynamics of colonisation of chickens by Campylobacter jejuni

Reference	BBS/E/I/00001165
Principal Investigator / Supervisor	Professor Mark Stevens
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	235,284
Status	Completed
Type	Institute Project
Start date	01/01/2006
End date	31/12/2008
Duration	36 months

Abstract

Campylobacter is the main cause of bacterial enteritis in the developed world. A major source of infection is considered to be the chicken and traditional methodologies for control, such as vaccines and using other bacteria to out compete the Campylobacter, or competitive exclusion, have little effect on flock contamination. Our preliminary studies, carried out with individually-tagged mutants, have shown that the process of colonisation is not as efficient or as simple as has been assumed, and has suggested that there are specific choke points for colonisation. Preliminary data suggest a range of selective processes which may be occurring during infection. The understanding of the process of colonisation is essential for the rational design of intervention strategies to reduce this reservoir of disease and the refinement of risk analyses of flock infection.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	Animal Health, Immunology, Microbial Food Safety, Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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