Award details

Analyses of the genome and phenotypes of Eimeria

Reference	BBS/E/I/00001143
Principal Investigator / Supervisor	Professor Martin Shirley
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	309,935
Status	Completed
Type	Institute Project
Start date	01/04/2003
End date	31/03/2006
Duration	36 months

Abstract

The aims of this project are to generate data that complement the needs for assembling the E. tenella genome and, from those data, derive a more comprehensive understanding of the organisation of individual chromosomes that, in conjunction with analyses of the progeny of a genetic cross, inform on the outcomes of recombination during the sexual phase of reproduction. The objectives of the project are to: 1. Extend the mapping of representative genes on the molecular karyotype to determine their chromosomal locations. Genes chosen initially will be those identified as comprising specific metabolic pathways. 2. Feed these data in to the assembly of the genome at the Sanger Institute. 3. Following on from previous studies by Rahmat Sheriff, focus on the organisation of chromosomes 3 and 4 ¿ a comprehensively assembly for these chromosomes will be expected to aid in the identification of regions that contribute to size polymorphisms. 4. Through collaboration, examine synteny between chromosomes of E. tenella and the sequences of other apicomplexans within the public domain. 5. Analyse the inheritance of markers in independent genetic crosses in E. tenella between the pathogenic Wey strain and the WisF96 hyper-abbreviated line and selection of recombinant progeny.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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