Award details

Improvement of FMD control by ethically acceptable methods based on scientifically validated assays and new knowledge on FMD vaccines and their impact

Reference	BBS/E/I/00001104
Principal Investigator / Supervisor	Professor David Paton
Co-Investigators / Co-Supervisors	Dr Paul Barnett
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	219,279
Status	Completed
Type	Institute Project
Start date	01/01/2004
End date	31/12/2008
Duration	60 months

Abstract

There is a strong desire to reduce reliance on large-scale culling of animals to control future outbreaks of FMD in EU Member States. As an alternative, it is proposed to use emergency vaccination and then to screen for residual infection using tests for antibodies to the non-structural proteins of FMD virus. It is intended to amend the policy on FMD control to enable such an approach to be used in the very near future. In reality, this means that current contingencies must be based on the use of existing vaccines, Therefore, this project seeks to address the specific gaps in our knowledge and technological ability with respect to the implementation of a vaccinate-to-live policy. The availability of adequate discriminatory diagnostic tests is the keystone of the new EU FMD control policy. The project is focused on the validation of NSP-based tests to discriminate unequivocally between infected and vaccinated animals, in order to allow the implementation of the new policy in the immediate term. Validation of existing and new NSP-tests as confirmatory tests will be a major output of this project.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	Animal Health, Immunology, Microbiology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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