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Identification of loci that encode immunoprotective antigens of Eimeria maxima through genetic linkage analysis
Reference
BBS/E/I/00001085
Principal Investigator / Supervisor
Professor Martin Shirley
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
98,248
Status
Completed
Type
Institute Project
Start date
22/10/2003
End date
21/10/2006
Duration
36 months
Abstract
A completely new strategy will be used to identify the loci that encode immunoprotective molecules of an antigenically complex protozoan pathogen. This work builds on the success of a 2 year BBSRC-funded pilot study and is driven by the need for sustainable, non drub-based, approaches for controlling coccidial parasites (Eimeria sp) in chickens. Our strategy makes use of the genetics of the parasite in combination with parasite killing by the immune host. This powerful dual approach has the crucial technical strength of directing analyses towards the immunoprotective antigens and away from the far greater majority of parasite antigens that induce non-protective responses in the host.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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