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Functional assessment of type III secreted Sop effector proteins from Salmonella in eukaryotic cells
Reference
BBS/E/I/00001035
Principal Investigator / Supervisor
Dr Edouard Galyov
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
26,876
Status
Completed
Type
Institute Project
Start date
01/10/2003
End date
30/09/2006
Duration
36 months
Abstract
Activities of salmonella outer proteins (Sops) that are involved in the induction of enteropathogenic responses in the infected host will be investigated using a combination of molecular and cell biology approaches. Each Sop protein (SopA, SopB and SopD) will be expressed in eukaryotic cells and cellular responses elicited by such expression will be assessed. Finally, phenotypes discovered in these in vitro experiments will be verified using experimental infections of eukaryotic cells with different relevant salmonella mutant strains.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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