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Award details
Avian Molecular Immunology
Reference
BBS/E/I/00001031
Principal Investigator / Supervisor
Dr John Young
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
880,083
Status
Completed
Type
Institute Project
Start date
01/04/2003
End date
30/06/2009
Duration
75 months
Abstract
1. To test whether RCAS/RNAi can be used to develop hypotheses about the regulation of B-cell development, which we anticipate will lead to collaborative applications for external funding; 2. To study the enhancement of humoral response to an antigen in ruminants by covalent coupling to CD40L; 3. To define the functions of B7 and CD28 in immune responses of chickens, so that they can be used for assessment of methods to improve the activation of antigen-presenting cells by vaccine delivery systems; 4. To define the functional effects of signalling by the TNFSF and costimulatory signals to antigen-presenting cells using microarrays.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
Animal Health, Immunology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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