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Tracing the origins of foot-and-mouth disease

Reference	BBS/E/I/00001004
Principal Investigator / Supervisor	Dr Donald King
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	99,030
Status	Completed
Type	Institute Project
Start date	01/07/2003
End date	30/06/2006
Duration	36 months

Abstract

Foot-and-mouth disease (FMD) can be caused by seven different serotypes of virus and within serotypes further subtypes can be identified. Different FMD virus serotypes and subtypes occur to varying extents in different parts of the world, some regions being endemically infected with multiple strains. The pattern of worldwide distribution of the different strains changes with the spread of different viruses and according to the types of disease control practised. Large-scale movements and trade of animals and animal products are the most important modes of viral transmission between regions, but air-borne and fomite derived spread also can occur. In addition, new strains of FMDV arise periodically. It is important to keep track of which FMDV strains occur where and how they have been introduced, so that new threats can be identified and appropriate decisions taken on import controls and on contingency planning including diagnostic preparedness and vaccine selection. The FMD World Reference Laboratory (WRL) at Pirbright receives new FMD virus isolates from all around the world. Genetic sequencing of these viruses allows us to precisely characterise new strains of FMDV and to relate outbreak strains of virus to strains already present in the WRL collection. This enables us to monitor the emergence and spread of FMD virus globally.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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