Award details

An investigation into host genetic resistance to Campylobacter colonisation in poultry

Reference	BBS/E/I/00000920
Principal Investigator / Supervisor	Professor Paul Barrow
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	7,450
Status	Completed
Type	Institute Project
Start date	01/01/2002
End date	31/12/2004
Duration	36 months

Abstract

Campylobacter is an intestinal commensal of poultry flocks and a major food-borne pathogen in man. Differences in the level of cloacal colonisation by C. jejuni have been found in the IAH inbred lines of chickens after challenge on the day-of-hatch, with line 61 being relatively resistant and line N relatively sensitive to colonisation. Quantitative measurement of Campylobacter in caeca and other tissues will provide further information about the observed differences. Genetic crosses between lines N and 61 will be established and analysed to identify any genomic regions that contain genes affecting the levels of colonisation. High resolution comparative maps will be constructed across regions of interest and used, together with database mining, to select positional candidates.

Summary

unavailable

Committee	Closed Committee - Agri-food (AF)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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