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Immunological mechanisms of protection against classical swine fever virus: Towards the development of new efficacious marker vaccines
Reference
BBS/E/I/00000917
Principal Investigator / Supervisor
Professor Tom Wileman
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
18,214
Status
Completed
Type
Institute Project
Start date
01/11/2001
End date
31/12/2005
Duration
50 months
Abstract
The high costs of a classical swine fever (CSF) outbreak, the social impact and resistance against destruction of pigs have led to reconsideration of emergency vaccination against CSF. The application of marker vaccines that can provide early protection might contribute to improved intervention and control strategies and might limit the duration and costs of an outbreak. The objective of this project is to understand the immune mechanisms underlying protection against CSF, in particular the mechanisms involved in early protection against clinical signs of CSF and in the reduction of (horizontal) virus transmission. The knowledge about relevant viral components and about the quality of the vaccine-induced immune response may contribute to the future development of new and safe marker vaccines that can induce a fast protective immune response.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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