Award details

Development of a safe, efficacious bluetongue virus vaccination strategy for Europe

Reference	BBS/E/I/00000908
Principal Investigator / Supervisor	Professor Philip Mellor
Co-Investigators / Co-Supervisors	Professor Peter Mertens
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	113,343
Status	Completed
Type	Institute Project
Start date	01/12/2001
End date	30/11/2004
Duration	36 months

Abstract

Bluetongue virus (BTV) has a track record of incursion into the EU and causing severe disease and financial losses to our livestock industry. However, the EU has no coherent vaccination policy which makes BTV incursions difficult or impossible to control. This project will enable an effective policy to be established for the first time by testing the existing live virus vaccines for efficacy and safety, and by providing clear science-based recommendations on their use or otherwise in Europe. The project will also seek to develop and produce inactivated vaccines conferring enhances protection using state of the art technology with engineered "virus-like particles" and slow release delivery systems. In addition, by sequencing live vaccine strains of BTV and wild strains isolated in the field around Europe, a database will be established to enable sourcing of European BTV incursions and early detection of vaccine breakdown thus facilitating targeting of control measures.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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