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Award details
Do strains of mouse adapted scrapie and BSE correlate with strains seen in the natural host?
Reference
BBS/E/I/00000867
Principal Investigator / Supervisor
Professor Nora Hunter
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
94,814
Status
Completed
Type
Institute Project
Start date
01/04/2001
End date
31/03/2007
Duration
72 months
Abstract
The aim of this project is to find out if passage of scrapie and of BSE through various species will change the phenotype of the diseases. The project uses transgenic mice expressing sheep or bovine PrP genes as models for these species and compares the results with mouse passage through mouse lines of differing PrP genotype. The results of this study will be relevant to the question of whether, if BSE has infected UK sheep, it will retain its characteristics which allow us to identify it easily or whether it will be changed by transmission between animals and across species barriers.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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