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Identification of immune subsets that contribute to IFNgamma-dependent protection against S. typhimurium in vivo
Reference
BBS/E/I/00000856
Principal Investigator / Supervisor
Dr Adrian Smith
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
142,420
Status
Completed
Type
Institute Project
Start date
01/11/2001
End date
30/06/2003
Duration
20 months
Abstract
The aim of this work is to identify the cell subsets that contribute to IFNg-dependent immunity to Salmonella typhimurium infection during primary and subsequent rechallenge infections. There are three main objectives addressed by this proposal. 1. Determination of the anti-Salmonella mechanism(s) mediated by natural killer (NK) cells 2. The minimal requirement for T cell subsets and the IFNg-mediated anti-Salmonella response 3. The interaction between different T cell subsets and the IFNg-mediated anti-Salmonella response.
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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