Award details

Identification of host cell proteins which interact with rinderpest virus

ReferenceBBS/E/I/00000840
Principal Investigator / Supervisor Dr Michael Baron
Co-Investigators /
Co-Supervisors
Institution The Pirbright Institute
DepartmentThe Pirbright Institute Department
Funding typeResearch
Value (£) 13,700
StatusCompleted
TypeInstitute Project
Start date 01/10/2000
End date 30/09/2003
Duration36 months

Abstract

This project involves mapping the domains of L that interact with viral proteins and investigating whether the L protein of RPV also interacts with specific host cell proteins. The objectives are to study the interaction of various domains of the L protein of rinderpest virus (RPV) with (1) the N, P and C proteins and (2) with elongation factor 1, actin, etc., i.e. with known proteins. If none of the specific proteins tested in (2) interact with the RPV L, we will screen an entire cDNA library of fusions for interaction with the L protein.The objectives are to study the interaction of various domains of the L protein with (1) the N, P and C proteins and (2) with elongation factor 1, actin, etc., i.e. with known proteins. If none of the specific proteins tested in (2) interact with the RPV L, we will screen an entire cDNA library of fusions for interaction with the L protein.

Summary

unavailable
Committee Closed Committee - Animal Sciences (AS)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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