BBSRC Portfolio Analyser
Award details
Microarray analysis of gene function and host interaction in Salmonella typhimurium (Salarray)
Reference
BBS/E/I/00000829
Principal Investigator / Supervisor
Dr N Bumstead
Co-Investigators /
Co-Supervisors
Institution
The Pirbright Institute
Department
The Pirbright Institute Department
Funding type
Research
Value (£)
66,640
Status
Completed
Type
Institute Project
Start date
01/12/2000
End date
30/11/2003
Duration
36 months
Abstract
The objectives of this project are: 1. The construction of a complete and definitive gene array for S.typhimurium based on its genomic sequence 2. Creation of a microarray of a selected set of chicken genes involved in host response to Salmonella infections. 3. Optimised procedures for the preparation of RNA, labeling and hybridisation for the Salmonella and chicken gene arrays 4. Gene expression profiles for S.typhimurium growing under different nutrient and redox conditions 5. Gene expression profiles for strains containing known mutations in genes affecting growth and virulence 6. Gene expression profiles for S.typhimurium genes and host genes expressed during adhesion and invasion of host cells 7. Gene expression profiles for S.typhimurium genes and host genes expressed in interactions between macrophages and S.typimurium
Summary
unavailable
Committee
Closed Committee - Agri-food (AF)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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