Award details

Avian MHC genes, molecules and functions

Reference	BBS/E/I/00000795
Principal Investigator / Supervisor	Professor Jim Kaufman
Co-Investigators / Co-Supervisors
Institution	The Pirbright Institute
Department	The Pirbright Institute Department
Funding type	Research
Value (£)	658,700
Status	Completed
Type	Institute Project
Start date	01/04/2000
End date	31/03/2003
Duration	36 months

Abstract

The aims of the project are to: 1. Characterise the expression and polymorphism of genes in the chicken MHC, relating these properties to function at the molecular level. 2. Map and characterise genes related to, interacting with or located close to chicken MHC genes, in particular those genes on the chicken MHC chromosome and paralogous regions 3. Develop reagents and assays to analyse the immune response of chickens at the cellular level (particularly T cells and NK cells) to pathogens and vaccines. 4. Identify epitopes in pathogens and vaccines that bind to chicken class I and class II molecules, as the basis for improvement of vaccines

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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